diff --git a/Source/Editor/SceneGraph/GUI/ActorTreeNode.cs b/Source/Editor/SceneGraph/GUI/ActorTreeNode.cs
index 14f11ceef..9cfe5b7bd 100644
--- a/Source/Editor/SceneGraph/GUI/ActorTreeNode.cs
+++ b/Source/Editor/SceneGraph/GUI/ActorTreeNode.cs
@@ -698,6 +698,10 @@ namespace FlaxEditor.SceneGraph.GUI
             if (thisHasScene != otherHasScene)
                 return false;
 
+            // Reject dragging actors between prefab windows (different roots)
+            if (!thisHasScene && ActorNode.Root != actorNode.Root)
+                return false;
+
             // Reject dragging parents and itself
             return actorNode.Actor != null && actorNode != ActorNode && actorNode.Find(Actor) == null;
         }